Rheumatic fever
Clinical trials for Rheumatic fever explained in plain language.
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Can two existing drugs stop rheumatic fever from scarring young hearts?
Disease control Not yet recruitingResearchers are running a Phase 3 trial to see whether hydroxychloroquine or corticosteroids can reduce heart valve damage in children and young people with acute rheumatic fever. The trial enrolls about 600 participants aged 4 to 25 who are hospitalized with confirmed valve infl…
Matched conditions: RHEUMATIC FEVER
Phase 3 • Sponsor: Starship Child Health, Te Toka Tumai Auckland • Aim: Disease control
Last updated Sep 21, 2026 17:00 UTC
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Could a monthly pill replace painful penicillin shots for rheumatic heart disease?
Disease control Not yet recruitingThis study will test if taking oral azithromycin pills for three days each month works as well as getting a monthly penicillin shot to prevent rheumatic heart disease from getting worse. The trial plans to enroll 474 Nigerian secondary school students aged 10-18 with mild or mode…
Matched conditions: RHEUMATIC FEVER
Sponsor: Ladoke Akintola University of Technology, Ogbomoso, Nigeria • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC