RETINITIS PIGMENTOSA (RP)

This is a very early study to check if a single gene therapy injection (called UGX202) is safe for people with advanced retinitis pigmentosa (RP), a rare genetic eye disease that causes vision loss. The study will enroll about 6 adults who have extremely low vision to receive the…

This study is testing a tiny electronic implant called PRIMA that is placed in the eye. It aims to restore some central vision for people who have lost it due to inherited retinal diseases like Stargardt disease and retinitis pigmentosa. The study will check if the implant is saf…

This early-stage trial is testing a new injection called ZM-02 for people with advanced retinitis pigmentosa, an inherited eye disease that causes progressive vision loss and has no effective treatment. The study will check if the injection is safe and if it can help preserve vis…

This study is testing whether a new drug called NPI-001 can slow down vision loss in adults with Usher syndrome, a rare genetic condition that causes both hearing and vision problems. Over 24 months, 80 participants will take either NPI-001 or a placebo (inactive substance) twice…

This study aims to see if a new type of wide-field eye scanner (OCTA) can help doctors better diagnose and monitor a range of eye diseases. It will involve 200 participants, some with conditions like macular degeneration or diabetic retinopathy and some healthy controls. Research…

This small pilot study is testing whether a safe, painless form of brain stimulation can temporarily improve how well adults with severe tunnel vision can get around. Participants will receive a brief session of either real or fake stimulation and then walk a course with obstacle…

This study looks back at medical records and eye scans from up to 200 people with inherited retinal diseases, which cause progressive vision loss. Researchers aim to understand how these diseases naturally change over time and how a person's specific genetic cause relates to thei…