Respiratory depression

This trial tests whether continuous pulse oximetry with wireless alerts to clinicians can reduce serious breathing complications (respiratory depression) after surgery. Patients on two surgical wards will be monitored continuously instead of every four hours. The goal is to see i…

After surgery, painkillers can slow breathing. This study tested a device that uses a mild electrical pulse on the skin to wake patients when their breathing stops for 10 seconds. Researchers enrolled 60 adults recovering from surgery to see if the system is practical and accepta…

This study compared two sedatives, dexmedetomidine and propofol, in 100 high-risk patients undergoing ERCP. The goal was to see which drug causes fewer breathing and heart problems. Researchers monitored vital signs closely to find the safer option for these vulnerable patients.

This early-stage study tests a new drug called ENA-001 in 36 healthy adults to see if it is safe and how the body processes it. Participants receive a single dose either through a vein or as a shot. The goal is to gather safety information before testing it in patients with respi…

This study looked at how a low dose of ketamine, a medicine often used for anesthesia, affects breathing and brain activity in 15 critically ill patients who were on breathing machines (ventilators) in the ICU. The goal was to see if ketamine could help stimulate breathing and im…

This study tested whether using a monitor that tracks breathing and oxygen levels (called IPI) can prevent dangerous oxygen drops during ERCP, a procedure to examine the bile ducts. 80 adults having elective ERCP under moderate sedation were randomly assigned to either standard m…