Relapsed or refractory large B-cell lymphoma
Clinical trials for Relapsed or refractory large B-cell lymphoma explained in plain language.
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Outpatient CAR T-Cell therapy shows promise for tough lymphoma
Disease control CompletedThis study tested a cancer treatment called axicabtagene ciloleucel (a CAR T-cell therapy) given with preventive steroids to 35 adults with large B-cell lymphoma that had returned or not responded to prior treatments. The goal was to see if giving the therapy in an outpatient set…
Matched conditions: RELAPSED OR REFRACTORY LARGE B-CELL LYMPHOMA
Phase 2 • Sponsor: Kite, A Gilead Company • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Double attack on blood cancer: stem cell transplant plus CAR-T shows promise
Disease control CompletedThis study tested a new approach for adults with a tough-to-treat type of blood cancer called large B-cell lymphoma that had returned or not responded to prior treatment. Participants first received a stem cell transplant using their own cells, followed by infusions of two types …
Matched conditions: RELAPSED OR REFRACTORY LARGE B-CELL LYMPHOMA
Phase 2 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Can a common arthritis drug tame CAR-T's dangerous side effects?
Symptom relief CompletedThis phase 2 trial tested whether adding the drug anakinra (Kineret) to standard CAR-T cell therapy could prevent nerve toxicity in 15 people with relapsed or refractory non-Hodgkin lymphoma. Participants received anakinra injections for a week alongside their CAR-T infusion. The…
Matched conditions: RELAPSED OR REFRACTORY LARGE B-CELL LYMPHOMA
Phase 2 • Sponsor: Marcela V. Maus, M.D.,Ph.D. • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC