Recurrent prostate cancer
Clinical trials for Recurrent prostate cancer explained in plain language.
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Can radiation boost a personalized prostate cancer vaccine?
Disease control CompletedResearchers are testing whether giving radiation therapy before sipuleucel-T, a personalized immunotherapy vaccine, works better than the vaccine alone in men with hormone-resistant prostate cancer that has spread. The trial enrolls about 51 participants and randomly assigns them…
Matched conditions: RECURRENT PROSTATE CANCER
Phase 2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Could a depression drug fight prostate cancer?
Disease control CompletedThis phase 2 trial tested phenelzine sulfate (Nardil), an antidepressant, in 26 men with prostate cancer that returned after initial treatment but hadn't spread. The goal was to see if the drug could lower PSA levels, a marker of cancer activity. Researchers measured how many pat…
Matched conditions: RECURRENT PROSTATE CANCER
Phase 2 • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Could an immunotherapy drug replace hormone therapy for some prostate cancers?
Disease control CompletedThis phase 2 trial tested the immunotherapy drug nivolumab (Opdivo) in 8 men whose prostate cancer had returned after surgery or radiation, shown by rising PSA levels. The men had specific genetic changes (MMR deficiency or CDK12 alteration) that might make their cancers more sen…
Matched conditions: RECURRENT PROSTATE CANCER
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New PET scan technique could map hidden prostate cancer recurrences
Diagnosis CompletedThis large registry study is testing whether a special type of PET scan, called PSMA-PET, can better detect where prostate cancer has returned after initial treatment. Thousands of men with suspected recurrent prostate cancer across Ontario will receive this scan. The goal is to …
Matched conditions: RECURRENT PROSTATE CANCER
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Diagnosis
Last updated Jul 19, 2026 00:00 UTC
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Grape extract shows promise for easing fatigue in prostate cancer patients
Symptom relief CompletedThis study tested whether a supplement made from muscadine grapes could reduce fatigue and improve quality of life in 106 men with prostate cancer who were already receiving hormone therapy (androgen deprivation therapy). Participants took either the grape extract or a placebo fo…
Matched conditions: RECURRENT PROSTATE CANCER
Phase 2 • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC