RECURRENT LYMPHOMA

This study is testing how well a drug called selpercatinib works for children and young adults with advanced or hard-to-treat cancers that have a specific genetic change in the RET gene. The drug is designed to block the growth of cancer cells with this change. Participants take …

This early-phase study aimed to test the safety and find the right dose of a two-drug immunotherapy (nivolumab and ipilimumab) for children, teens, and young adults whose cancers had returned or stopped responding to standard treatments. The drugs work by helping the patient's ow…

This large national trial is testing whether choosing cancer drugs based on the specific genetic changes found in a patient's tumor is more effective than standard approaches. It is for adults with advanced solid tumors, lymphoma, or multiple myeloma that have progressed after at…

This study is testing a new oral drug called Elimusertib in children and young adults whose solid tumors have come back or stopped responding to standard treatments. The main goals are to find the safest dose and see if the drug can shrink tumors, particularly in certain types of…

This study aims to understand how often advanced cancer patients experience severe weight loss and loss of appetite, a condition called cachexia. Researchers are also measuring the emotional and psychological stress this causes for both the patients and their primary family careg…