RAS MUTATION
Clinical trials for RAS MUTATION explained in plain language.
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New hope for advanced cancers: experimental drug RSC-1255 enters human trials
Disease control Recruiting nowThis early-phase trial tests an experimental drug called RSC-1255, given alone or with hydroxychloroquine, in adults with advanced solid tumors (such as lung, colon, pancreatic, or brain cancer) that have not responded to or cannot tolerate standard treatments. The study has two …
Matched conditions: RAS MUTATION
Phase: PHASE1 • Sponsor: RasCal Therapeutics, Inc. • Aim: Disease control
Last updated May 26, 2026 09:02 UTC
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New pill targets tough cancers: early trial seeks safer doses
Disease control Recruiting nowThis early-phase study tests an experimental drug called PAS-004 in about 48 adults with advanced solid tumors that have certain gene mutations (RAS, NF1, or RAF). The main goal is to find a safe dose and understand side effects. Participants take the drug by mouth daily for up t…
Matched conditions: RAS MUTATION
Phase: PHASE1 • Sponsor: Pasithea Therapeutics Corp. • Aim: Disease control
Last updated May 26, 2026 08:33 UTC
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New pill targets Hard-to-Treat cancers with RAS mutations
Disease control Recruiting nowThis early-phase study tests a new oral drug, AN9025, in people with advanced solid tumors that have specific RAS gene mutations. The main goal is to check the drug's safety and find the right dose. About 91 participants will take the drug daily and be monitored closely for side …
Matched conditions: RAS MUTATION
Phase: PHASE1 • Sponsor: Adlai Nortye Biopharma Co., Ltd. • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New hope for advanced colorectal cancer: study tests smarter drug switch based on blood test
Disease control Recruiting nowThis study is for people with advanced colorectal cancer that has a certain genetic makeup (RAS/BRAF wild type) in the tumor but shows a different genetic change (RAS mutation) in a blood test. The goal is to see if a combination of chemotherapy (FOLFIRI) plus a drug called bevac…
Matched conditions: RAS MUTATION
Phase: PHASE3 • Sponsor: Azienda USL Reggio Emilia - IRCCS • Aim: Disease control
Last updated May 18, 2026 12:10 UTC
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New hope for hard-to-treat cancers: drug combo targets genetic weakness
Disease control Recruiting nowThis study tests a new drug called TNG462, given with other cancer medicines, for people with pancreatic or lung cancer that has a specific genetic change (MTAP loss). The goal is to find safe doses and see if the combination shrinks tumors. About 183 adults with advanced cancer …
Matched conditions: RAS MUTATION
Phase: PHASE1, PHASE2 • Sponsor: Tango Therapeutics, Inc. • Aim: Disease control
Last updated May 18, 2026 12:09 UTC
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Scientists launch massive effort to unlock secrets of rare genetic disorders
Knowledge-focused Recruiting nowThis study aims to learn more about a group of genetic conditions called RASopathies, which affect development and can cause heart defects, learning problems, and a higher risk of cancer. Researchers will collect blood, tissue, and medical information from up to 1,000 participant…
Matched conditions: RAS MUTATION
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated May 26, 2026 09:20 UTC