R/R AML
Clinical trials for R/R AML explained in plain language.
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Can a new combo drug tame childhood leukemia that Won't quit?
Disease control Not yet recruitingThis trial is investigating whether a new drug called sonrotoclax, when combined with other anti-cancer medicines, is safe and effective for children and adolescents with acute myeloid leukemia (AML) or B-cell acute lymphoblastic leukemia (ALL) that has returned or not responded …
Matched conditions: R/R AML
Phase 1/2 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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Can a common drug boost Chemo's power against Hard-to-Treat leukemia?
Disease control Not yet recruitingThis trial is testing whether adding hydroxyurea to a standard chemotherapy combination can improve outcomes for adults with acute myeloid leukemia (AML) that has returned or not responded to treatment. The study is conducted in two parts: first to find the safest dose of hydroxy…
Matched conditions: R/R AML
Phase 1/2 • Sponsor: Christer C Nilsson • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Engineered immune cells take on tough leukemia in early trial
Disease control Not yet recruitingThis early-phase trial tests a new type of cell therapy called CAR-ITNK cells, designed to target two proteins (CD70 and CLL1) on leukemia cells. It will enroll 30 adults with relapsed or refractory acute myeloid leukemia (AML) who have not responded to standard treatments. Parti…
Matched conditions: R/R AML
Early phase 1 • Sponsor: Tongji Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC