Progressive supranuclear palsy (PSP)
Clinical trials for Progressive supranuclear palsy (PSP) explained in plain language.
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New spinal injection drug tested for rare brain disorder
Disease control CompletedThis early-stage trial tested a drug called NIO752 in 59 people with progressive supranuclear palsy (PSP), a rare brain disorder that affects movement and balance. The drug was given as a spinal injection to see if it is safe and how the body processes it. The main goal was to ch…
Matched conditions: PROGRESSIVE SUPRANUCLEAR PALSY (PSP)
Phase 1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New PET tracers aim to spot tau tangles in rare brain disease
Diagnosis CompletedThis early-phase study tests two new imaging drugs, [18F]ABBV-964i and [18F]ABBV-965i, designed to light up tau protein buildup in the brain during a PET scan. Tau buildup is linked to Progressive Supranuclear Palsy (PSP), a rare movement and thinking disorder. The trial includes…
Matched conditions: PROGRESSIVE SUPRANUCLEAR PALSY (PSP)
Early phase 1 • Sponsor: Invicro • Aim: Diagnosis
Last updated Jul 12, 2026 00:00 UTC
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Can art therapy improve life for people with PSP?
Symptom relief CompletedResearchers at Baylor College of Medicine are studying whether weekly art therapy can ease symptoms and improve quality of life for people with progressive supranuclear palsy (PSP), a rare brain disorder that affects movement, balance, and eye control. About 20 participants with …
Matched conditions: PROGRESSIVE SUPRANUCLEAR PALSY (PSP)
Sponsor: Baylor College of Medicine • Aim: Symptom relief
Last updated Sep 18, 2026 00:00 UTC
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Can a sleep drug help people with PSP rest better?
Symptom relief CompletedThis study tested two sleep medications (suvorexant and zolpidem) against a placebo in 40 adults with Progressive Supranuclear Palsy (PSP). The goal was to see if targeting the brain's wake-promoting system could improve sleep quality and daytime well-being. Each person tried all…
Matched conditions: PROGRESSIVE SUPRANUCLEAR PALSY (PSP)
Phase 4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Sep 03, 2026 00:00 UTC