Progesterone resistance
Clinical trials for Progesterone resistance explained in plain language.
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Hormone blockers and letrozole tested to spare uterus in early endometrial cancer
Disease control Recruiting nowResearchers are testing a combination of a gonadotropin-releasing hormone agonist injection and the drug letrozole in obese women with early-stage endometrial cancer that has not responded to progestin. The goal is to see if this hormone-blocking approach can shrink tumors and al…
Matched conditions: PROGESTERONE RESISTANCE
Phase 2/3 • Sponsor: Xiaojun Chen • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Hormone combo tested as Fertility-Sparing option for early uterine cancer
Disease control Recruiting nowResearchers test whether a combination of GnRHa and letrozole can shrink early endometrial cancer or atypical hyperplasia in non-obese patients who have not responded to progestin therapy. The trial compares this regimen with Diane-35 plus metformin. About 80 participants receive…
Matched conditions: PROGESTERONE RESISTANCE
Phase 2/3 • Sponsor: Xiaojun Chen • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC