Primary mediastinal [thymic] large B-cell lymphoma (PMBCL)

Clinical trials for Primary mediastinal [thymic] large B-cell lymphoma (PMBCL) explained in plain language.

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New combo aims to boost CAR T-Cell success in tough lymphomas

Disease control Ongoing

This phase 2 study tests whether adding the drug acalabrutinib to the CAR T-cell therapy lisocabtagene maraleucel (liso-cel) can improve outcomes for people with aggressive B-cell lymphomas that have come back or not responded to treatment. About 28 adults will receive acalabruti…

Matched conditions: PRIMARY MEDIASTINAL [THYMIC] LARGE B-CELL LYMPHOMA (PMBCL)

Phase 2 • Sponsor: Patrick C. Johnson, MD • Aim: Disease control

Last updated Jun 27, 2026 09:00 UTC

Primary mediastinal [thymic] large B-cell lymphoma (PMBCL)

Get alerted when new Primary mediastinal [thymic] large B-cell lymphoma (PMBCL) trials appear

New combo aims to boost CAR T-Cell success in tough lymphomas