Primary mediastinal B cell lymphoma
Clinical trials for Primary mediastinal B cell lymphoma explained in plain language.
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Can a single shot build a cancer army inside the body?
Cure Not yet recruitingThis trial tests an experimental gene therapy called UB-VV400, designed to instruct a person's own cells to become CAR T cells that target CD22 on B-cell cancers. It is given together with rapamycin, a drug that may help the therapy work better. The study enrolls adults with rela…
Matched conditions: PRIMARY MEDIASTINAL B CELL LYMPHOMA
Phase 1/2 • Sponsor: Umoja Biopharma • Aim: Cure
Last updated Aug 19, 2026 00:00 UTC
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Engineered immune cells take on stubborn lymphoma
Disease control Not yet recruitingThis study tests a new approach using a mix of gene-modified immune cells (CAR-T cells) that target multiple proteins found on B cell lymphoma cells. The goal is to see if this combination is safe and can shrink tumors in patients whose cancer has not responded to standard treatm…
Matched conditions: PRIMARY MEDIASTINAL B CELL LYMPHOMA
Phase 1/2 • Sponsor: Shenzhen Geno-Immune Medical Institute • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Which Pre-CAR-T chemo is safer? new trial aims to find out
Disease control Not yet recruitingThis trial tests whether bendamustine causes fewer severe side effects than the standard fludarabine/cyclophosphamide combination when given before CAR-T cell therapy for B-cell lymphoma. About 92 people will be randomly assigned to one of the two chemotherapy regimens. The main …
Matched conditions: PRIMARY MEDIASTINAL B CELL LYMPHOMA
Phase 2 • Sponsor: Swiss Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New CAR-T therapy aims to tackle tough blood cancers
Disease control Not yet recruitingThis trial tests a new treatment called SHB-02-CD19, which uses a patient's own immune cells engineered to attack cancer cells that have a protein called CD19. It is for children and adults with B-cell cancers (like leukemia or lymphoma) that have come back or not responded to at…
Matched conditions: PRIMARY MEDIASTINAL B CELL LYMPHOMA
Phase 1/2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Brain fog after lymphoma: study probes lasting cognitive effects of chemotherapy
Knowledge-focused Not yet recruitingThis study looks at thinking skills, memory, and quality of life in people who are 3 to 5 years past successful treatment for Hodgkin lymphoma or certain types of B-cell lymphoma. Participants take a series of tests and questionnaires once during a regular follow-up visit. The go…
Matched conditions: PRIMARY MEDIASTINAL B CELL LYMPHOMA
Sponsor: Fondazione Italiana Linfomi - ETS • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC