PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA (PCNSL)
Clinical trials for PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA (PCNSL) explained in plain language.
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New hope for aggressive brain cancer: 3-drug combo targets relapsed lymphoma
Disease control Recruiting nowThis study tests a combination of three drugs (pomalidomide, an anti-PD-1 antibody, and selinexor) in people whose primary central nervous system lymphoma has come back or stopped responding to treatment. The goal is to see if this drug cocktail can shrink tumors and improve surv…
Matched conditions: PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA (PCNSL)
Phase: PHASE2 • Sponsor: Beijing Tongren Hospital • Aim: Disease control
Last updated May 26, 2026 07:34 UTC
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New drug cocktail shows promise for rare brain cancer
Disease control Recruiting nowThis study tests a combination of four drugs (PD-1 inhibitor, rituximab, methotrexate, and orelabrutinib) in 50 people with newly diagnosed or relapsed lymphoma that has spread to the brain. The main goal is to see how many patients remain cancer-free one year after treatment. Th…
Matched conditions: PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA (PCNSL)
Phase: PHASE2 • Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New drug duo targets Hard-to-Treat brain cancer
Disease control Recruiting nowThis study tests whether combining two drugs, epcoritamab and ibrutinib, is safe for people with central nervous system (CNS) lymphoma that has returned or not responded to treatment. About 26 adults with this rare brain cancer will take part. The main goal is to find the best do…
Matched conditions: PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA (PCNSL)
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 20, 2026 11:53 UTC
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New drug targets Hard-to-Treat blood cancers in early trial
Disease control Recruiting nowThis early-stage study tests a new drug called NX-2127 in adults with certain blood cancers (like CLL or lymphoma) that have returned or not improved after other treatments. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. About …
Matched conditions: PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA (PCNSL)
Phase: PHASE1 • Sponsor: Nurix Therapeutics, Inc. • Aim: Disease control
Last updated May 18, 2026 12:11 UTC
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New drug targets Hard-to-Treat blood cancers in early trial
Disease control Recruiting nowThis study tests an experimental drug called NX-5948 in adults with certain blood cancers (like CLL or lymphoma) that have come back or stopped responding to treatment. The drug works by breaking down a protein that helps cancer cells grow. The main goals are to find a safe dose …
Matched conditions: PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA (PCNSL)
Phase: PHASE1 • Sponsor: Nurix Therapeutics, Inc. • Aim: Disease control
Last updated May 18, 2026 12:09 UTC
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Scientists hunt for clues in the blood to unlock brain lymphoma mysteries
Knowledge-focused Recruiting nowThis study aims to find differences in blood chemicals and immune cells between people with primary central nervous system lymphoma (a rare brain cancer), those with a similar lymphoma outside the brain, and healthy volunteers. Researchers will collect blood samples and track pat…
Matched conditions: PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA (PCNSL)
Sponsor: Ting YANG • Aim: Knowledge-focused
Last updated May 26, 2026 07:24 UTC