Primary central nervous system lymphoma
Clinical trials for Primary central nervous system lymphoma explained in plain language.
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Can a targeted drug combo outsmart brain lymphoma?
Disease control CompletedThis early-stage trial is testing whether adding the targeted drug orelabrutinib to a standard chemotherapy regimen can safely treat newly diagnosed primary central nervous system lymphoma (PCNSL), a rare type of lymphoma that starts in the brain or spinal cord. The study will en…
Matched conditions: PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase 1 • Sponsor: Huashan Hospital • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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New combo therapy shows promise for older brain cancer patients
Disease control CompletedThis early-stage trial tested the safety of the drug nivolumab given after standard chemotherapy in 14 older adults (65 and up) with primary CNS lymphoma, a rare brain cancer. The goal was to see if adding nivolumab could help keep the cancer from coming back for at least 2 years…
Matched conditions: PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase 1 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New drug combo shows promise against rare brain cancer
Disease control CompletedThis completed study looked at 136 people with newly-diagnosed primary central nervous system lymphoma (a rare brain cancer). Researchers compared standard chemo alone versus chemo plus the targeted drug orelabrutinib. The goal was to see if the combination improved tumor shrinka…
Matched conditions: PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA
Sponsor: Huashan Hospital • Aim: Disease control
Last updated Jun 26, 2026 17:57 UTC