Premature ovarian failure
Clinical trials for Premature ovarian failure explained in plain language.
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Could a Blood-Stimulating drug revive failing ovaries?
Disease control CompletedThis pilot trial tests whether a drug called G-CSF, given as a short course of injections, can improve markers of ovarian reserve in women aged 25-40 with premature ovarian insufficiency (POI). The main question is whether treatment can lower FSH levels, raise AMH, and increase a…
Matched conditions: PREMATURE OVARIAN FAILURE
Phase 2 • Sponsor: Trio Fertility • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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Could cell-derived vesicles restart the ovaries? a new trial investigates
Disease control CompletedThis early-phase trial tests whether injecting tiny particles called extracellular vesicles, derived from bone marrow stem cells, directly into the ovary is safe for women with premature ovarian failure. The study includes 10 women aged 20–38 who have had no menstrual period for …
Matched conditions: PREMATURE OVARIAN FAILURE
Phase 1/2 • Sponsor: Royan Institute • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Stem cell gene therapy for early menopause: 2.5-Year Follow-Up shows promise
Disease control CompletedThis study followed 86 women under 40 with premature ovarian failure (early menopause) who had received a one-time gene therapy using their own stem cells. The goal was to check long-term safety and see if hormone levels and fertility improved over 2.5 years. No new treatment was…
Matched conditions: PREMATURE OVARIAN FAILURE
Sponsor: Ukraine Association of Biobank • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Cord blood plasma could repair thin uterine lining
Disease control CompletedThis study tested whether platelet-rich plasma from umbilical cord blood can thicken the endometrium (uterine lining) in women with Asherman's syndrome or endometrial atrophy. Fifteen women received an injection of the plasma into the uterine wall during a hysteroscopy, along wit…
Matched conditions: PREMATURE OVARIAN FAILURE
Phase 2 • Sponsor: Fundación IVI • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Hormone therapy may boost sex life in early menopause, study hopes
Knowledge-focused CompletedThis study follows 135 women with premature ovarian failure (early menopause) to see if hormone replacement therapy improves their sexual quality of life. Participants fill out questionnaires about sexual function and well-being before starting treatment and again 6 months later.…
Matched conditions: PREMATURE OVARIAN FAILURE
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC