Positron emission tomography

This study tests whether adding precise, high-dose radiation (SBRT) to standard hormone therapy can delay cancer progression in men with prostate cancer that has spread to 1-3 spots. About 118 participants will be randomly assigned to get SBRT plus standard care or standard care …

Researchers are testing whether a single injection of a radioactive tracer, followed by a PET/CT scan, can clearly show primary tumors and any spread in adults with suspected or known SSTR-related cancers. The study will measure how well the tracer highlights lesions and calculat…

This trial tests whether a single injection of a radioactive tracer called 68Ga/18F-Exendin 4 can improve PET/CT scans for finding tumors that carry GLP-1 receptors. Researchers will enroll 500 adults with suspected or known tumors, including insulinomas, and measure how brightly…

Researchers are testing whether a new PET/CT imaging agent, 68Ga/18F-Pentixafor/Pentixather, can accurately detect primary tumors and metastases in people with CXCR4-related diseases, including certain lymphomas and other cancers. The study will enroll 200 participants who have s…

Researchers are testing whether a radioactive tracer called 68Ga/18F-PSMA/PSFA can improve PET/CT scans for finding tumors in people with PSMA-related cancers, including prostate and liver cancer. The study will enroll 500 adults with suspected, newly diagnosed, or previously tre…

This study is testing a special type of PET/CT scan that looks for a protein called PD-L1 on cancer cells. The goal is to see if this scan can find tumors and their spread more accurately than standard imaging. About 500 adults with suspected or known PD-L1-related cancers will r…

This trial tests whether a new imaging tracer called FAPI, used with PET/CT scans, can better detect primary tumors and metastases in people with FAP-related diseases. Researchers will give participants a single injection of the tracer and then perform imaging to measure how much…

This Phase 3 trial is testing whether combining a special PET scan (PSMA PET) with MRI can detect prostate cancer better than standard methods. About 204 men with suspected prostate cancer will receive the combined imaging, and results will be compared to biopsy findings. The goa…

This study tests whether a special PET/CT scan using a tracer called 68Ga-Pentixafor can accurately diagnose primary aldosteronism, a common cause of high blood pressure. The scan aims to identify which adrenal gland is overproducing the hormone aldosterone, potentially replacing…

This trial evaluates a radioactive tracer called 68Ga-DOTA/NOTA-FAPI-04, given as a single injection before a PET/CT scan, to see if it can better identify primary tumors and metastases in people with various cancers. Researchers will measure how strongly the tracer accumulates i…

This early-stage study tests a new radioactive tracer called [11C]CHDI-00491009 to see if it can safely and accurately detect harmful protein clumps (mutant huntingtin) in the brains of people with Huntington's disease. The study involves 27 participants, including healthy volunt…

This early-phase study tests a new way to use PET scans to measure inflammation in both the liver and brain at the same time. Researchers will scan 12 adults with fatty liver disease using two different tracers (18F-FDG and 18F-DPA-714) to see if the new method can reliably detec…

This study uses special brain scans (PET, SPECT, and MRI) to look for a marker that shows how Parkinson's disease changes over time. Researchers will scan 44 people with Parkinson's to see if a compound called BU99008 can highlight brain cell activity linked to the disease. The g…

This study uses advanced brain scans (PET and MRI) to examine serotonin activity in people with Parkinson's disease. Researchers will compare brain images from 42 participants at different stages of the disease. The goal is to find biological markers that could lead to new treatm…