Plaque, atherosclerotic

This study tests if a drug called inclisiran can reduce fatty plaque buildup in the arteries of people who recently had a heart attack and have high cholesterol. About 318 adults will receive either inclisiran or standard care, and doctors will use special imaging to measure plaq…

This study tests a daily pill (obicetrapib plus ezetimibe) to see if it can reduce fatty plaque buildup in the arteries of 300 adults with heart disease. Participants must already be on cholesterol-lowering therapy but still have high LDL cholesterol and measurable plaque. The tr…

Researchers are testing a noninvasive ultrasound method called ARFI to see if it can detect features of carotid plaque that raise stroke risk. The study includes adults with narrowed carotid arteries, some with symptoms and some without. By measuring plaque characteristics, the t…

This study is developing an artificial intelligence system to analyze CT scans of the heart. The goal is to automatically detect and measure dangerous plaque that can cause heart attacks. Researchers will compare the AI's findings with detailed imaging tests and track patient out…

This study was designed to test a new catheter that takes two types of pictures inside heart arteries at the same time—using sound and light. The goal was to see if this hybrid approach is safer and better at identifying fatty plaques that could cause heart attacks compared to st…