PILON FRACTURE
Clinical trials for PILON FRACTURE explained in plain language.
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New injection could stop arthritis before it starts after ankle break
Prevention Recruiting nowThis study tests whether injecting N-Acetylcysteine (NAC) into the ankle joint shortly after a severe fracture can prevent cartilage cells from dying. About 30 adults with high-energy pilon fractures will receive either NAC or a placebo during their staged surgery. The goal is to…
Matched conditions: PILON FRACTURE
Phase: PHASE4 • Sponsor: University of Missouri-Columbia • Aim: Prevention
Last updated May 26, 2026 10:08 UTC
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New study aims to find best ankle surgery for frail seniors
Symptom relief Recruiting nowThis study looks at two different surgeries for treating broken ankles in frail older adults (age 60+). One method uses a rod inside the bone, and the other uses plates and screws. The goal is to see which approach helps patients feel better and recover more easily. About 172 peo…
Matched conditions: PILON FRACTURE
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Symptom relief
Last updated May 19, 2026 12:00 UTC