PI3K GENE MUTATION
Clinical trials for PI3K GENE MUTATION explained in plain language.
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First human trial launches for precision drug targeting a common cancer mutation
Disease control Recruiting nowThis is the first study in people testing a new drug called OKI-219, designed to target a specific genetic mutation (PI3KαH1047R) found in some advanced cancers. The main goals are to find a safe dose, see how the body processes the drug, and check for early signs that it might h…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE1 • Sponsor: OnKure, Inc. • Aim: Disease control
Last updated Apr 02, 2026 14:58 UTC
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Personalized pills target root cause of painful vascular growths
Disease control Recruiting nowThis trial is testing two different oral medications for people with abnormal, non-cancerous growths of blood or lymph vessels (vascular malformations). The goal is to see if a year of treatment can reduce patients' most bothersome symptoms and shrink the growths. The specific dr…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE2 • Sponsor: Murdoch Childrens Research Institute • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC