PI3K GENE MUTATION
Clinical trials for PI3K GENE MUTATION explained in plain language.
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New hope for rare blood vessel disorders: targeted drugs enter trial
Disease control Recruiting nowThis study tests two targeted drugs (alpelisib and mirdametinib) in 50 people aged 2 and older with vascular malformations—abnormal blood or lymph vessels. Participants receive 48 weeks of treatment based on their genetic mutation type. The goal is to see if these drugs improve e…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE2 • Sponsor: Murdoch Childrens Research Institute • Aim: Disease control
Last updated May 17, 2026 06:24 UTC
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New precision drug targets Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis early-phase study tests a new drug, OKI-219, designed to block a specific cancer-driving mutation (PI3KαH1047R) found in some advanced solid tumors and breast cancers. About 200 adults whose cancer has this mutation will receive OKI-219 alone or combined with other anti-canc…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE1 • Sponsor: OnKure, Inc. • Aim: Disease control
Last updated May 11, 2026 20:38 UTC