PI3K GENE MUTATION
Clinical trials for PI3K GENE MUTATION explained in plain language.
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New drug targets Hard-to-Treat cancers with PI3K mutation
Disease control OngoingThis early-stage trial tests a new drug called OKI-219 in people with advanced solid tumors or breast cancer that have a specific PI3K gene mutation. The drug is designed to block the mutant protein and slow cancer growth. Up to 200 participants will receive OKI-219 alone or comb…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE1 • Sponsor: OnKure, Inc. • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Gene-Guided drugs aim to shrink brain tumors
Disease control OngoingThis phase 2 trial tests whether genetic testing can help doctors pick the right targeted drug for people whose solid tumors have spread to the brain. About 50 participants with specific gene mutations (like NTRK, ROS1, CDK, PI3K, or KRAS G12C) will receive one of four drugs: abe…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC