PI3K GENE MUTATION
Clinical trials for PI3K GENE MUTATION explained in plain language.
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New hope for rare blood vessel disorders: targeted drugs enter trial
Disease control Recruiting nowThis study tests two targeted drugs (alpelisib and mirdametinib) in 50 people aged 2 and older with vascular malformations—abnormal blood or lymph vessels. The drugs aim to shrink or improve these growths by blocking specific genetic signals. Participants take the drug for 48 wee…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE2 • Sponsor: Murdoch Childrens Research Institute • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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New precision drug targets Hard-to-Treat cancers in early human trial
Disease control Recruiting nowThis study tests a new drug called OKI-219 in people with advanced solid tumors or breast cancer that have a specific change in the PI3K gene. The trial has two parts: first, finding the safest dose of OKI-219 alone, then testing it in combination with other cancer drugs. About 2…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE1 • Sponsor: OnKure, Inc. • Aim: Disease control
Last updated Apr 29, 2026 15:03 UTC