PHASE 1
Clinical trials for PHASE 1 explained in plain language.
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Engineered immune cells take on hard-to-treat melanoma in early trial
Disease control Recruiting nowThis early-phase study tests a new type of cell therapy for people with advanced melanoma that has not responded to standard treatments. The therapy uses a patient's own immune cells (NK cells) that have been engineered to recognize and attack a protein called PRAME found on mela…
Matched conditions: PHASE 1
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 10:35 UTC
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Engineered immune cells take on tough kidney cancer
Disease control Recruiting nowThis early-phase study tests a new treatment for advanced clear cell kidney cancer that has stopped responding to standard therapies. The treatment uses specially engineered immune cells (CAR NK cells) from a donor, designed to target cancer cells and resist the tumor's defenses.…
Matched conditions: PHASE 1
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 10:23 UTC
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Healthy volunteers help Fine-Tune new drug formulation
Knowledge-focused Recruiting nowThis early-stage study in 16 healthy adults aims to compare how a new tablet form of the experimental drug PF-07799933 is absorbed versus the current version. It also checks if a high-fat meal or an acid-reducing drug changes absorption. No treatment benefit is expected; the goal…
Matched conditions: PHASE 1
Phase: PHASE1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated May 26, 2026 10:24 UTC