Peyronie disease
Clinical trials for Peyronie disease explained in plain language.
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Can a gentler injection schedule straighten the curve in Peyronie's disease?
Disease control OngoingThis trial tests a step-wise treatment for Peyronie's disease, a condition causing penile curvature and pain. Men receive up to four series of collagenase injections, with mild in-office modeling, plus daily use of a traction device and sildenafil. If response is inadequate, up t…
Matched conditions: PEYRONIE DISEASE
Phase 4 • Sponsor: Charitable Union for the Research and Education of Peyronie's Disease • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Can a second injection fix penile curvature?
Disease control OngoingThis study tests whether a drug called Xiaflex (collagenase clostridium histolyticum) is safe and effective for men with Peyronie's disease who have already tried platelet-rich plasma (PRP) injections. Twelve men with stable penile curvature between 30 and 90 degrees will receive…
Matched conditions: PEYRONIE DISEASE
Phase 4 • Sponsor: University of Miami • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New injection shows promise for straightening penile curvature
Disease control OngoingThis study tested whether adding Fibrorestil® injections to standard care (traction therapy and pills) can better reduce penile curvature in men with Peyronie's disease. 38 men with stable curvature between 30 and 90 degrees participated. The main goal was to measure curvature ch…
Matched conditions: PEYRONIE DISEASE
Sponsor: Lyx Institute • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC