PERTUSSIS

This early-stage study tested a new whooping cough vaccine given as a nasal spray. 48 healthy adult men received either the vaccine or a placebo to check safety and immune response. The goal is to develop a single-dose nasal vaccine that can protect very young infants, who are mo…

This study tested a new vaccine called BK1310 in 267 healthy infants to see if it protects against tetanus, diphtheria, pertussis, polio, and bacterial meningitis. The vaccine was given as three shots and compared to existing vaccines. The goal was to check if the new vaccine wor…

This early-stage study tested a higher dose of a new live whooping cough vaccine (BPZE1) in 54 healthy adults aged 18-32. The goal was to see if the vaccine is safe and can temporarily live in the nose to potentially prevent infection. Researchers monitored side effects and check…

This study tested a booster dose of the DTaP vaccine (BK1301) in 446 adolescents aged 11-12 who had already received the vaccine series as children. The goal was to confirm the booster effectively strengthens immunity against diphtheria, tetanus, and pertussis (whooping cough). R…

This study looked at 200 mothers and their babies to understand how the whooping cough vaccine given during pregnancy protects infants. Researchers measured antibody levels in mothers and in umbilical cord blood, as well as in babies after their own vaccines. The goal was to find…