OSA - obstructive sleep apnea

This trial tests whether a combination of two sleep medications, eszopiclone and lemborexant, can help people who have both obstructive sleep apnea and insomnia. The idea is that these drugs may raise the brain's threshold for waking up, allowing more stable breathing during slee…

This study tests an injection called XW003 in 140 obese adults with obstructive sleep apnea who already use a breathing machine (PAP). The goal is to see if the drug reduces breathing pauses during sleep and helps with weight loss. Participants will receive either the drug or a p…

This phase 3 trial tests an injectable drug called XW003 (Ecnoglutide) in 140 obese adults with obstructive sleep apnea who do not use CPAP machines. The goal is to see if the drug reduces breathing pauses during sleep and helps with weight loss. Participants receive either the d…

This study looks at whether a weight-loss procedure called Endoscopic Sleeve Gastroplasty (ESG), combined with healthy eating and exercise, can improve obstructive sleep apnea (OSA) in people with obesity. About 74 adults with moderate to severe OSA will be randomly assigned to r…

This study tests whether extra support—like personalized mask fitting, monthly phone calls, and a tracking app—helps stroke patients with sleep apnea use their CPAP machine more consistently during rehab. About 250 participants will be randomly assigned to either this intensive s…

This study looks at whether treating obstructive sleep apnea (OSA) with a CPAP machine can improve asthma control in people with difficult-to-treat asthma. Eighty adults will be randomly assigned to receive CPAP, no OSA treatment, or serve as a reference group without OSA. The go…

This study looks at whether simple equations can accurately predict the right CPAP pressure for Thai people with obstructive sleep apnea, compared to the standard overnight lab test. About 150 participants will have a sleep study to check which equation works best. The goal is to…

This study looks at how obstructive sleep apnea (OSA) affects thinking, memory, and other brain functions in adults. Researchers will follow 30 people with newly diagnosed OSA for 12 months to see if using a breathing device (positive airway pressure therapy) helps protect the br…

This study looks at sleep quality in 100 people with atrial fibrillation (AFib) who are scheduled for a heart procedure called pulmonary vein isolation. Participants will have four non-invasive sleep tests—two before and two after the procedure—to measure breathing, heart rate, a…