Ocular graft versus host disease
Clinical trials for Ocular graft versus host disease explained in plain language.
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Can a new eye drop soothe the burning dryness of ocular GVHD?
Disease control Recruiting nowThis Phase 3 trial tests whether an experimental eye drop called d-MAPPS can reduce eye surface damage and ease symptoms like dryness and discomfort in adults with chronic ocular graft-versus-host disease (oGVHD), a complication of stem cell transplants. Participants will use the…
Matched conditions: OCULAR GRAFT VERSUS HOST DISEASE
Phase 3 • Sponsor: Regenerative Ocular Immunobiologics LLC • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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New eye drop offers hope for dry eye in transplant patients
Symptom relief Recruiting nowThis study tests an experimental eye drop (rhPRG4) to see if it safely eases dry eye symptoms in people with ocular graft-versus-host disease (oGVHD), a complication after bone marrow transplant. About 15 adults with moderate to severe dry eye will receive both the active drop an…
Matched conditions: OCULAR GRAFT VERSUS HOST DISEASE
Phase 2 • Sponsor: Lubris Bio Pty Ltd • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Scientists hunt for biomarkers to unlock rare eye disease treatments
Knowledge-focused Recruiting nowThis study aims to find biological markers (biomarkers) in blood, tears, and eye cells from 110 adults with seven rare eye diseases. Researchers will compare these markers between patients and healthy controls to see if they differ and if they relate to disease symptoms. The goal…
Matched conditions: OCULAR GRAFT VERSUS HOST DISEASE
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC