NSCLC
Clinical trials for NSCLC explained in plain language.
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New drug combo tested for Tough-to-Treat lung cancer
Disease control TerminatedThis early-stage study tested the safety and initial effectiveness of two new drugs, AK119 and AK112, given alone or with chemotherapy, for people with a specific type of advanced lung cancer (EGFR-mutant NSCLC) that had stopped responding to standard targeted therapy. The trial …
Matched conditions: NSCLC
Phase: PHASE1, PHASE2 • Sponsor: Akeso • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Experimental drug tested for Tough-to-Treat cancers
Disease control TerminatedThis study tested an experimental drug called VLS-101 (zilovertamab vedotin) in 102 people with advanced solid tumors that had spread and stopped responding to previous treatments. The trial aimed to see if the drug could shrink tumors and was safe for cancers including breast, l…
Matched conditions: NSCLC
Phase: PHASE2 • Sponsor: VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New targeted drug tested for Tough-to-Treat lung cancers
Disease control TerminatedThis study tested a new type of targeted cancer drug called MYTX-011 in people with advanced non-small cell lung cancer (NSCLC) that had progressed after standard treatments. The main goals were to find a safe dose and see if the drug could shrink tumors, especially in patients w…
Matched conditions: NSCLC
Phase: PHASE1 • Sponsor: Mythic Therapeutics • Aim: Disease control
Last updated Mar 13, 2026 15:06 UTC
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Researchers track drug levels in blood to understand lung cancer treatment response
Knowledge-focused TerminatedThis study aims to understand how the amount of pembrolizumab (an immunotherapy drug) in a patient's blood relates to their treatment outcomes for non-small cell lung cancer. Researchers will monitor drug levels and immune cell activity in about 80 patients who are receiving pemb…
Matched conditions: NSCLC
Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Could a simple blood test replace painful biopsies for lung cancer?
Knowledge-focused TerminatedThis study aimed to see if a simple blood test (liquid biopsy) could be as accurate as a traditional tissue biopsy for finding specific genetic changes in lung cancer. Researchers compared results from both methods in 21 patients with advanced lung cancer who had not yet started …
Matched conditions: NSCLC
Phase: NA • Sponsor: Centre Oscar Lambret • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC