Neurotoxicity
Clinical trials for Neurotoxicity explained in plain language.
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Could adding chemo to radiation tame Slow-Growing brain tumors?
Disease control OngoingThis phase 3 trial compares radiation therapy alone versus radiation plus the chemotherapy drug temozolomide for people with symptomatic or progressive low-grade gliomas. The study enrolled 540 adults and aims to see if adding chemo improves how long patients live without their t…
Matched conditions: NEUROTOXICITY
Phase 3 • Sponsor: Eastern Cooperative Oncology Group • Aim: Disease control
Last updated Jun 26, 2026 14:25 UTC
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Can a gentler anesthesia cocktail protect a child's developing brain?
Prevention OngoingThe TREX trial tests whether a low-dose combination of sevoflurane, remifentanil, and dexmedetomidine leads to better long-term brain development than standard-dose sevoflurane in children under 2 who need anesthesia for at least 2 hours. Researchers will randomly assign 450 chil…
Matched conditions: NEUROTOXICITY
Phase 3 • Sponsor: Murdoch Childrens Research Institute • Aim: Prevention
Last updated Sep 12, 2026 00:00 UTC