NEUROMUSCULAR DISEASES
Clinical trials for NEUROMUSCULAR DISEASES explained in plain language.
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Cell therapy shows promise in slowing duchenne muscular dystrophy
Disease control OngoingThis study tests a cell therapy called deramiocel (CAP-1002) in 106 boys and young men with Duchenne muscular dystrophy (DMD), a genetic disease that weakens muscles over time. Participants receive either deramiocel or a placebo every 3 months for a year, then all can receive der…
Matched conditions: NEUROMUSCULAR DISEASES
Phase: PHASE3 • Sponsor: Capricor Inc. • Aim: Disease control
Last updated May 26, 2026 03:15 UTC
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Could a simple breathing device slow ALS cough decline?
Disease control OngoingThis study tests if using a mechanical insufflation device (BiWaze Cough) twice daily for 6 months can slow the loss of cough strength in people with early ALS. Twenty adults with ALS will use the device at home with a caregiver's help. Researchers will measure changes in peak co…
Matched conditions: NEUROMUSCULAR DISEASES
Phase: NA • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated May 26, 2026 03:10 UTC
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New drug shows promise for SMA patients in major trial
Disease control OngoingThis study tests whether adding taldefgrobep alfa to standard SMA treatments can improve muscle function in people with spinal muscular atrophy. About 269 participants, both walkers and non-walkers, will receive either the drug or a placebo for 48 weeks. The goal is to see if the…
Matched conditions: NEUROMUSCULAR DISEASES
Phase: PHASE3 • Sponsor: Biohaven Pharmaceuticals, Inc. • Aim: Disease control
Last updated May 18, 2026 12:02 UTC
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Mind-Controlled typing: new headset tested for ALS patients
Knowledge-focused OngoingThis study is testing a new, comfortable headset that reads brain signals to help people with ALS type on a virtual keyboard. The goal is to see if the headset is easy to set up and use in daily life. Five people with ALS will try the device, and researchers will measure setup ti…
Matched conditions: NEUROMUSCULAR DISEASES
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated May 26, 2026 03:07 UTC
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MRI scans could replace painful biopsies for muscle diseases
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to improve how doctors diagnose neuromuscular diseases (like muscular dystrophy) by using whole-body MRI scans instead of invasive muscle biopsies. Researchers will collect MRI data from 1,000 patients across 14 centers to identify patterns of muscle damage. The g…
Matched conditions: NEUROMUSCULAR DISEASES
Sponsor: Ottawa Hospital Research Institute • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC