NEPHROTIC SYNDROME IN CHILDREN

This study tests if dupilumab can help children aged 6-18 with severe nephrotic syndrome, a kidney disease that causes swelling and protein in urine. Participants get injections of dupilumab or a placebo every 2-4 weeks for 6 months, while slowly reducing their steroid dose. The …

This study tests a noninvasive device that gently stimulates a nerve in the ear to help children with steroid-resistant nephrotic syndrome, a kidney condition that doesn't respond to standard steroids. The goal is to see if this approach is safe, tolerable, and can reduce inflamm…

This study tests a new drug called SG301, given as a shot under the skin, for children aged 6-18 with nephrotic syndrome that keeps coming back or requires steroids. The goal is to see if it can safely reduce relapses and help kids stay off steroids longer. About 30 children will…

This small pilot study is testing whether a gentle, non-invasive nerve stimulation device worn on the ear can help children with a frequently relapsing kidney disease. The goal is to see if this approach can reduce disease flare-ups and the need for strong steroid medications. Re…

This study helps people with nephrotic syndrome and related kidney diseases find clinical trials that may be a good fit for their specific condition. Researchers use detailed molecular information from each participant to recommend targeted therapies being tested in other studies…

This study interviews 150 children, adults, and parents about their experiences with swelling caused by Nephrotic Syndrome. Researchers will use the information to create a survey that helps test new medications. No treatment is given; the goal is to better understand symptoms.