Neoadjuvant treatment
Clinical trials for Neoadjuvant treatment explained in plain language.
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Can a Four-Part combo before surgery wipe out head and neck tumors?
Cure OngoingResearchers are testing whether giving low-dose radiotherapy, the immunotherapy drug tislelizumab, and two chemotherapy drugs before surgery helps people with locally advanced head and neck squamous cell carcinoma. The trial enrolls adults with untreated, operable stage III to IV…
Matched conditions: NEOADJUVANT TREATMENT
Phase 2 • Sponsor: Fifth Affiliated Hospital, Sun Yat-Sen University • Aim: Cure
Last updated Sep 11, 2026 00:00 UTC
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New hope: drug before surgery may shrink ovarian tumors
Disease control OngoingThis study tests whether the drug olaparib, given before surgery, can shrink tumors in women with recurrent ovarian cancer that has come back after at least 6 months. About 71 participants will receive either olaparib or standard chemotherapy before surgery. Researchers will meas…
Matched conditions: NEOADJUVANT TREATMENT
Phase 2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New study aims to predict who can skip surgery for rectal cancer
Knowledge-focused OngoingThis pilot study is testing whether regular MRI scans and blood tests can accurately track how rectal cancer responds to pre-surgery treatment. The goal is to develop a way to predict complete remission without needing surgery. Forty adults with locally advanced rectal cancer wil…
Matched conditions: NEOADJUVANT TREATMENT
Sponsor: Jena University Hospital • Aim: Knowledge-focused
Last updated Aug 08, 2026 00:03 UTC
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Blood test may predict lung cancer outcomes before surgery
Knowledge-focused OngoingThis study is looking at 100 people with stage IIIA lung cancer who are getting treatment before surgery. Researchers want to see if a blood test that looks for tumor DNA (ctDNA) can predict how well patients do. If the tumor DNA disappears after treatment, it might mean a better…
Matched conditions: NEOADJUVANT TREATMENT
Sponsor: Fundación GECP • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC