NASH
Clinical trials for NASH explained in plain language.
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New drug shows promise against fatty liver in early trial
Disease control CompletedThis study tested a new medicine called DD01 in 67 overweight or obese adults with a type of fatty liver disease (MASLD or MASH). The goal was to see if DD01 could safely reduce liver fat over 48 weeks compared to a placebo. Participants were randomly assigned to receive either D…
Matched conditions: NASH
Phase: PHASE2 • Sponsor: Neuraly, Inc. • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New drug shows promise for fatty liver in early trial
Disease control CompletedThis study tested an experimental drug called elobixibat in 47 adults with nonalcoholic fatty liver disease (NAFLD) or its more severe form, NASH. The main goal was to see if the drug could lower bad cholesterol (LDL-C) compared to a placebo over 16 weeks. Researchers also monito…
Matched conditions: NASH
Phase: PHASE2 • Sponsor: Albireo • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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Plant power: natural supplement shows promise for fatty liver
Disease control CompletedThis study looked at whether taking phytosterols (natural plant compounds) for 3 months could improve liver health, cholesterol, and insulin levels in 27 adults with nonalcoholic fatty liver disease (NAFLD). Participants took daily supplements while researchers tracked changes in…
Matched conditions: NASH
Phase: NA • Sponsor: University of Jordan • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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Blood tests may replace painful liver biopsies for diabetes patients
Diagnosis CompletedThis study looked at whether two blood tests, eLIFT and FibroMeter, can accurately detect advanced liver fibrosis (scarring) in people with type 2 diabetes. The researchers compared these blood tests to a liver scan (FibroScan) and, in some cases, a liver biopsy. The goal is to f…
Matched conditions: NASH
Phase: NA • Sponsor: Nantes University Hospital • Aim: Diagnosis
Last updated May 26, 2026 05:46 UTC
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Liver disease Patients' vaccine response under the microscope
Knowledge-focused CompletedThis study looked at how well COVID-19 vaccines protect people with chronic liver disease, including hepatitis B, C, NAFLD, and NASH. Researchers followed 233 adults for 6 months, checking their immune response through blood tests and questionnaires. The goal was to see if liver …
Matched conditions: NASH
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated May 26, 2026 05:43 UTC
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Can a phone app help NASH patients get fit?
Knowledge-focused CompletedThis study tested whether a mobile health exercise program called EL-FIT is practical, safe, and acceptable for people with nonalcoholic steatohepatitis (NASH), a type of liver disease. Seventeen adults with NASH took part. The main goal was to see if at least half of them would …
Matched conditions: NASH
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC