NASAL POLYPS
Clinical trials for NASAL POLYPS explained in plain language.
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New insights into a severe asthma treatment
Disease control CompletedThis study aimed to understand how the drug mepolizumab affects inflammation in the nose, lungs, and body of adults with severe, hard-to-treat asthma. Researchers followed 15 patients for one year to see how their symptoms, lung function, and specific biological markers changed w…
Matched conditions: NASAL POLYPS
Sponsor: Istituti Clinici Scientifici Maugeri SpA • Aim: Disease control
Last updated Apr 02, 2026 14:58 UTC
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Year-Long shot tested to shrink nasal polyps and improve breathing
Disease control CompletedThis study tested an investigational long-acting injection called depemokimab for adults with chronic sinusitis and troublesome nasal polyps. The goal was to see if regular injections over one year could safely reduce polyp size, improve nasal blockage, and lessen symptoms like l…
Matched conditions: NASAL POLYPS
Phase: PHASE3 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Apr 02, 2026 14:56 UTC
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New drug aims to shrink nasal polyps and improve breathing
Disease control CompletedThis Phase 3 study tested an injectable drug called depemokimab in 264 adults with chronic sinusitis and troublesome nasal polyps. The goal was to see if the drug could safely reduce polyp size and improve symptoms like nasal blockage and loss of smell over 52 weeks. Participants…
Matched conditions: NASAL POLYPS
Phase: PHASE3 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Radical sinus surgery tested to stop nasal polyp regrowth
Disease control CompletedThis study tested whether a more extensive sinus surgery approach works better than standard surgery for people with chronic sinusitis and nasal polyps. Researchers compared two surgical methods in 110 Chinese patients to see which one better controls symptoms and reduces polyp r…
Matched conditions: NASAL POLYPS
Phase: NA • Sponsor: Zheng Liu • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Scientists probe hidden role of immune signal in stubborn sinus condition
Knowledge-focused CompletedThis study aimed to understand how a specific immune system signal called IL-5 affects different cells inside nasal polyps, a condition causing chronic sinus problems. Researchers analyzed tissue samples from 30 people with nasal polyps and aspirin-sensitive asthma, as well as he…
Matched conditions: NASAL POLYPS
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Mar 03, 2026 14:06 UTC