MUSCLE-INVASIVE UROTHELIAL CARCINOMA
Clinical trials for MUSCLE-INVASIVE UROTHELIAL CARCINOMA explained in plain language.
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New drug duo aims to shrink bladder tumors before surgery
Disease control Recruiting nowThis early-phase trial tests whether combining two immune-boosting drugs, atezolizumab and tiragolumab, can help control bladder cancer when given before surgery to remove the bladder and tumor. It includes 10 adults with muscle-invasive bladder cancer who cannot take the standar…
Matched conditions: MUSCLE-INVASIVE UROTHELIAL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 23, 2026 11:59 UTC
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Personalized cancer vaccine + immunotherapy aims to stop bladder cancer return
Disease control Recruiting nowThis phase 2 trial tests whether adding a personalized cancer vaccine (autogene cevumeran) to the immunotherapy nivolumab can prevent high-risk bladder cancer from coming back after surgery. About 62 participants will receive either the combination or nivolumab alone. The study o…
Matched conditions: MUSCLE-INVASIVE UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 22, 2026 12:00 UTC
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Bladder cancer Drug's nerve side effect under microscope
Knowledge-focused Recruiting nowThis study looks at how enfortumab vedotin, a drug for advanced bladder cancer, may affect nerves. Researchers will use nerve tests and patient reports to measure changes over 9-15 weeks. The goal is to better understand and track nerve damage caused by the treatment. About 50 ad…
Matched conditions: MUSCLE-INVASIVE UROTHELIAL CARCINOMA
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:08 UTC