Muscle invasive bladder urothelial carcinoma
Clinical trials for Muscle invasive bladder urothelial carcinoma explained in plain language.
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Gene therapy joins forces with chemo and immunotherapy to fight bladder cancer
Disease control Not yet recruitingThis phase 2 trial tests whether adding a gene therapy called nadofaragene firadenovec to standard chemotherapy and immunotherapy can improve outcomes for people with muscle invasive bladder cancer before they have their bladder removed. The gene therapy is placed directly into t…
Matched conditions: MUSCLE INVASIVE BLADDER UROTHELIAL CARCINOMA
Phase 2 • Sponsor: University of Washington • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC
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Can two drugs spare the bladder in aggressive bladder cancer?
Disease control Not yet recruitingResearchers are testing whether combining enfortumab vedotin and pembrolizumab can shrink muscle-invasive bladder cancer enough to avoid removing the bladder or using radiation. The trial enrolls 25 adults with confirmed muscle-invasive urothelial carcinoma that has not spread. P…
Matched conditions: MUSCLE INVASIVE BLADDER UROTHELIAL CARCINOMA
Phase 2 • Sponsor: University of Utah • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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New drug cocktail aims to spare bladders in tough cancer
Disease control Not yet recruitingThis phase 2 trial tests a combination of two drugs (toripalimab and RC48-ADC) plus radiation in 45 people with HER2-positive muscle-invasive bladder cancer. The goal is to see if this approach can eliminate the cancer and allow patients to keep their bladder after initial chemot…
Matched conditions: MUSCLE INVASIVE BLADDER UROTHELIAL CARCINOMA
Phase 2 • Sponsor: Tongji Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC