MELANOMA (SKIN)
Clinical trials for MELANOMA (SKIN) explained in plain language.
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Could an On-Off drug schedule tame advanced melanoma?
Disease control OngoingThis early study tested a new way of giving three drugs (encorafenib, binimetinib, and nivolumab) to people with advanced BRAF-mutant melanoma. The goal was to see if an on/off schedule could help control the cancer while reducing side effects. Only 14 adults with stage IIIC to I…
Matched conditions: MELANOMA (SKIN)
Phase: EARLY_PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 26, 2026 03:10 UTC
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Can a 4-Week drug course keep melanoma from returning?
Disease control OngoingThis study looked at whether giving high-dose interferon alfa-2b for four weeks helps prevent melanoma from coming back in people whose cancer was removed by surgery. About 1,150 patients with stage II or III melanoma took part. The goal was to see if the drug improves how long p…
Matched conditions: MELANOMA (SKIN)
Phase: PHASE3 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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New vaccine combo shows promise in advanced skin cancer trial
Disease control OngoingThis study tests two experimental cancer vaccines, SCIB1 and iSCIB1+, given alongside standard immunotherapy drugs (nivolumab with ipilimumab or pembrolizumab) for people with advanced melanoma that cannot be removed by surgery. The goal is to see if adding the vaccines is safe a…
Matched conditions: MELANOMA (SKIN)
Phase: PHASE2 • Sponsor: Scancell Ltd • Aim: Disease control
Last updated May 20, 2026 11:54 UTC