Malignant tumors
Clinical trials for Malignant tumors explained in plain language.
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Can a Two-Drug combo outsmart childhood cancers that resist treatment?
Disease control CompletedThis early-stage trial is testing whether combining two chemotherapy drugs, temozolomide and topotecan, is safe and tolerable for children and adolescents with malignant tumors that have returned or not responded to standard treatments. The study aims to find the highest safe dos…
Matched conditions: MALIGNANT TUMORS
Phase 1 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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New drug duo shows promise against tough cancers
Disease control CompletedThis study tested a combination of two drugs, LBL-007 and tislelizumab, in 98 adults with advanced solid tumors. The goal was to see if the combo is safe, tolerable, and effective at shrinking tumors. Researchers also looked at how the drugs move through the body and whether they…
Matched conditions: MALIGNANT TUMORS
Phase 1/2 • Sponsor: Nanjing Leads Biolabs Co.,Ltd • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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PET scan clue may predict tumor treatment success
Knowledge-focused CompletedThis study looked at whether a special PET/CT scan done before treatment could predict how well radioactive seed implants would work for malignant tumors. Researchers reviewed data from 41 patients with 69 tumors. They found that a measurement called Metabolic Tumor Volume (MTV) …
Matched conditions: MALIGNANT TUMORS
Sponsor: Jiangxi Provincial Cancer Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC