Locked-in syndrome
Clinical trials for Locked-in syndrome explained in plain language.
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Mind over matter: brain implant lets paralyzed patients control computers
Disease control Recruiting nowThis study tests the safety and feasibility of the BrainGate2 system, a brain-computer interface. Tiny sensors are placed in the brain area that controls movement, allowing people with tetraplegia (paralysis of all four limbs) to control a computer cursor or other assistive devic…
Matched conditions: LOCKED-IN SYNDROME
Sponsor: Leigh R. Hochberg, MD, PhD. • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Mind-Controlled computer: brain implant gives voice to the paralyzed
Disease control Recruiting nowThis study tests a brain implant that records brain signals to help people with locked-in syndrome control a computer. Two participants will have 128 electrodes placed on their brain surface. Researchers will train them to use the system at home for one year, aiming for accurate …
Matched conditions: LOCKED-IN SYNDROME
Sponsor: UMC Utrecht • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Mind-Reading implant aims to give a voice to the paralyzed
Knowledge-focused Recruiting nowThis trial tests a brain-computer interface called CortiCom, which is surgically placed on the brain's surface to record signals related to speech and arm movement. The goal is to see if these signals can be decoded to control software and devices, potentially helping people with…
Matched conditions: LOCKED-IN SYNDROME
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Aug 23, 2026 00:00 UTC
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Mind-Reading brain chip could give voice to the voiceless
Knowledge-focused Recruiting nowThis early-stage study tests a brain implant called BrainGate in just 3 people with severe paralysis or speech loss from conditions like ALS or spinal cord injury. The goal is to see if the device is safe and can let users control a computer cursor or other tools by thought alone…
Matched conditions: LOCKED-IN SYNDROME
Sponsor: Leigh R. Hochberg, MD, PhD. • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Mind reading? scientists decode imagined chinese speech from brain activity
Knowledge-focused Recruiting nowThis study investigates whether brain surface recordings can decode Mandarin Chinese speech, including tones, from imagined speech. About 50 participants with brain tumors or epilepsy will have temporary electrodes placed during surgery, and 10 people with severe speech loss will…
Matched conditions: LOCKED-IN SYNDROME
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Mind-Reading device aims to give voice to the speechless
Knowledge-focused Recruiting nowThis study tests a brain implant that reads signals from the brain to help people who have lost the ability to speak fluently communicate through a computer just by trying to talk. It involves up to 2 participants with conditions like spinal cord injury or ALS. The main goal is t…
Matched conditions: LOCKED-IN SYNDROME
Sponsor: Leigh R. Hochberg, MD, PhD. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC