LOCALLY ADVANCED LUNG NON-SMALL CELL CARCINOMA
Clinical trials for LOCALLY ADVANCED LUNG NON-SMALL CELL CARCINOMA explained in plain language.
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New drug combo targets tough lung cancer mutation
Disease control Recruiting nowThis study tests a combination of two drugs, sotorasib and trastuzumab deruxtecan, in people with advanced non-small cell lung cancer that has a specific KRAS G12C mutation. The goal is to see if the combination is safe, tolerable, and effective at shrinking tumors. About 37 adul…
Matched conditions: LOCALLY ADVANCED LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 03:55 UTC
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Custom-Made cancer vaccine shows promise in advanced tumors
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, combined with the immunotherapy drug pembrolizumab, for people with advanced solid tumors (like breast, lung, or skin cancer). The goal is to see if the combination is safe and helps the immune syst…
Matched conditions: LOCALLY ADVANCED LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New combo radiation therapy aims to boost survival in advanced lung cancer
Disease control Recruiting nowThis study tests whether adding a precise, high-dose radiation treatment (SBRT) to the tumor before standard chemoradiation and immunotherapy can help people with locally advanced lung cancer live longer. About 474 adults whose lung cancer has spread to nearby lymph nodes but can…
Matched conditions: LOCALLY ADVANCED LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 18, 2026 11:59 UTC
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Smarter radiation: new study aims to cut lung cancer treatment side effects
Symptom relief Recruiting nowThis study tests a smarter way to give radiation to people with lung cancer. Normally, the radiation plan is made before treatment starts, but tumors can shrink during treatment, which may expose healthy tissue to unnecessary radiation. In this study, the radiation plan is update…
Matched conditions: LOCALLY ADVANCED LUNG NON-SMALL CELL CARCINOMA
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Symptom relief
Last updated May 26, 2026 04:23 UTC
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Can personalized chemoradiation protect lung cancer Patients' hearts?
Knowledge-focused Recruiting nowThis study looks at how chemoradiation for locally advanced lung cancer affects the heart. Researchers will track heart injury and fitness in 100 patients, using each person's risk profile to tailor treatment and potentially reduce heart damage. The goal is to learn how to better…
Matched conditions: LOCALLY ADVANCED LUNG NON-SMALL CELL CARCINOMA
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 04:11 UTC