LARGE B-CELL LYMPHOMA (LBCL)
Clinical trials for LARGE B-CELL LYMPHOMA (LBCL) explained in plain language.
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New CAR-T therapy shows promise for aggressive blood cancer
Disease control Recruiting nowThis study tests a treatment called CD19 CAR-T therapy for people newly diagnosed with a fast-growing type of blood cancer called high-risk large B-cell lymphoma. The therapy uses a patient's own immune cells, modified to attack cancer cells. The main goal is to see if this treat…
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE2 • Sponsor: Zhejiang University • Aim: Disease control
Last updated May 26, 2026 04:05 UTC
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New drug cocktail offers hope for older lymphoma patients who Can't handle chemo
Disease control Recruiting nowThis study tests a combination of four drugs (Pola-ZR-Glo) in 30 older adults (70+) with untreated large B-cell lymphoma who are too frail for standard chemo. The goal is to see if this gentler approach can control the cancer and improve quality of life. Researchers will track ho…
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated May 26, 2026 03:59 UTC
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Could a simple pill make CAR-T therapy work better for lymphoma patients?
Disease control Recruiting nowThis early-phase study tests whether adding an experimental drug called CLS-015 to standard CAR-T cell therapy can improve outcomes for people with large B-cell lymphoma whose disease is stable or progressing. The drug aims to reverse immune-suppressing effects in the tumor envir…
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE1 • Sponsor: Tel-Aviv Sourasky Medical Center • Aim: Disease control
Last updated May 26, 2026 03:54 UTC
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New hope for lymphoma patients: experimental drug enters phase 2 trial
Disease control Recruiting nowThis study tests a new drug called surovatamig in 240 adults with B-cell non-Hodgkin lymphoma that has come back or not responded to at least two prior treatments. The goal is to see if the drug can shrink or eliminate tumors. Participants receive the drug alone, and researchers …
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Phase: PHASE2 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Cheaper CAR-T therapy could expand access for lymphoma patients
Disease control Recruiting nowThis study is testing a lower-cost, lab-made version of CAR-T cell therapy for adults with relapsed or refractory large B-cell lymphoma. The treatment uses a patient's own immune cells, modified to target and kill cancer cells. The goal is to see if this academic approach is safe…
Matched conditions: LARGE B-CELL LYMPHOMA (LBCL)
Sponsor: N.N. Alexandrov National Cancer Centre • Aim: Disease control
Last updated May 18, 2026 12:03 UTC