LARGE B-CELL LYMPHOMA
Clinical trials for LARGE B-CELL LYMPHOMA explained in plain language.
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Engineered immune cells take on tough lymphoma in early trial
Disease control OngoingThis early-phase study tests a new type of CAR T-cell therapy for adults with large B-cell lymphoma that has come back or not responded to treatment. The therapy uses a patient's own immune cells, modified to better recognize and attack cancer cells. The main goals are to find a …
Matched conditions: LARGE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 23, 2026 18:08 UTC
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New CAR-T therapy shows promise for tough blood cancers
Disease control OngoingThis study tests a new treatment called rapcabtagene autoleucel (YTB323) for adults with certain blood cancers like chronic lymphocytic leukemia, small lymphocytic lymphoma, diffuse large B-cell lymphoma, and acute lymphoblastic leukemia. The treatment uses a patient's own immune…
Matched conditions: LARGE B-CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 17, 2026 12:06 UTC
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Engineered immune cells target tough blood cancers in new trial
Disease control OngoingThis study tests FDA-approved CAR-T cell therapy in 150 children and adults with certain blood cancers that have come back or not responded to treatment. Participants receive their own immune cells that have been reprogrammed to attack cancer cells. The goal is to see how many pa…
Matched conditions: LARGE B-CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Jun 09, 2026 12:07 UTC
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CAR t therapy aims to snuff out hidden lymphoma cells
Disease control OngoingThis study tests whether a personalized cell therapy called liso-cel can stop large B-cell lymphoma from returning in patients who still have traces of cancer DNA after initial treatment. About 50 adults who are in remission but test positive for lymphoma DNA will receive their o…
Matched conditions: LARGE B-CELL LYMPHOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 08, 2026 13:08 UTC