KRAS G12C
Clinical trials for KRAS G12C explained in plain language.
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New pill takes on tough cancers: first human trial begins
Disease control OngoingThis early-phase study tests a new oral drug called TT125-802 in 50 adults with advanced solid tumors (like lung cancer) that have not responded to standard treatments. The main goals are to check the drug's safety, find the right dose, and see if it can shrink tumors. It is a fi…
Matched conditions: KRAS G12C
Phase: PHASE1 • Sponsor: TOLREMO therapeutics AG • Aim: Disease control
Last updated Jun 22, 2026 11:57 UTC
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New vaccine combo shows promise for Hard-to-Treat cancers
Disease control OngoingThis early-stage trial tests a custom-made vaccine using a patient's own immune cells, designed to target specific cancer markers (EphA2 and KRAS mutations). The vaccine is given together with two immunotherapy drugs to boost the immune system's attack on tumors. The study includ…
Matched conditions: KRAS G12C
Phase: PHASE1 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated Jun 16, 2026 12:51 UTC
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New immunotherapy targets tough pancreatic cancers in early trial
Disease control OngoingThis early-phase trial tests an experimental immunotherapy called ELI-002 7P in people with pancreatic or other solid tumors that have specific KRAS or NRAS gene mutations. The treatment aims to train the immune system to attack cancer cells. About 158 participants will receive t…
Matched conditions: KRAS G12C
Phase: PHASE1, PHASE2 • Sponsor: Elicio Therapeutics • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC