Iron overload
Clinical trials for Iron overload explained in plain language.
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Herbal remedy vs. standard drug: a new hope for thalassemia iron overload?
Disease control CompletedThis trial compares an experimental herbal formulation called Irochel against the standard medication deferoxamine in managing iron overload caused by repeated blood transfusions in thalassemia patients. The study involves 132 children and adolescents aged 10 to 16 with transfusi…
Matched conditions: IRON OVERLOAD
Phase 3 • Sponsor: Hamdard University • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Could an iron scavenger slow ALS?
Disease control CompletedThis study tested whether deferiprone, a drug that removes excess iron, could safely slow the progression of ALS. Researchers gave the drug to 23 adults with ALS for several months. The goal was to see if reducing iron buildup in the brain might protect nerve cells and delay wors…
Matched conditions: IRON OVERLOAD
Phase 2 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Simple blood tests may spot liver damage in thalassemia kids
Diagnosis CompletedThis study looked at 100 children with beta-thalassemia major and iron overload to see if simple blood tests (ferritin and hepcidin) can detect liver scarring (fibrosis) as accurately as other non-invasive methods. Researchers measured these blood markers and compared them to ult…
Matched conditions: IRON OVERLOAD
Sponsor: Tanta University • Aim: Diagnosis
Last updated Jun 26, 2026 14:15 UTC
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Lab study tests Iron-Binding drug on Parkinson's and ALS cells
Knowledge-focused CompletedThis completed study looked at how the drug deferiprone affects blood cells from 90 people with Parkinson's disease, ALS, or healthy volunteers. Researchers measured markers of oxidative stress and iron levels in the lab. The goal was to better understand these diseases, not to t…
Matched conditions: IRON OVERLOAD
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC