Intracranial aneurysm

Researchers compare two versions of a mesh stent used to treat unruptured brain aneurysms. One version has a special coating and is paired with a single blood-thinning drug; the other is the standard device paired with two blood-thinning drugs. The trial measures tiny brain lesio…

This trial tests whether dimethyl fumarate, an oral anti-inflammatory medication, can reduce inflammation in the walls of unruptured brain aneurysms. About 60 adults with small, unruptured aneurysms will receive either the drug or a placebo for six months. Using advanced MRI scan…

This study tested a new device called SINOMED IAS in 203 people with wide-necked brain aneurysms. The device is a stent placed inside the artery to block blood flow into the aneurysm, helping it heal. The main goal was to see if the aneurysm was successfully closed at 6 months af…

This study tested a device called Trenza for treating brain aneurysms. It involved 150 people aged 18 to 80 with a single saccular aneurysm between 6 and 12 mm. The goal was to see if the device could safely block the aneurysm from blood flow and prevent strokes.

This study tested a new medical wire, called the Tarvos Microguidewire, used during surgery on blood vessels in the brain. The wire helps doctors guide other tools to the right spot. Researchers looked back at records of 121 patients who had this wire used in their surgery for co…

This study tested a temporary device called Comaneci that helps doctors place coils in wide-necked brain aneurysms. 90 patients were treated and followed for up to 6 months to check safety and how well the aneurysm was sealed. The goal was to see if the device works well in every…

This study tested a new stent called Tonbridge for treating brain aneurysms (weak spots in blood vessels). It involved 204 people aged 18 to 80 who needed a stent to help place coils inside the aneurysm. The goal was to see if the new stent works as well as an existing device at …

This study tested a new medical device called the Tonbridge flow diverter to treat brain aneurysms (weak spots in blood vessels). The device is placed inside the artery to redirect blood flow away from the aneurysm, helping it heal. The trial included 142 people aged 18 to 80 wit…

This study compared two procedures for treating unruptured brain aneurysms: traditional coiling (using tiny coils to block blood flow) and a newer method using a flow diverter stent. 91 adults with specific types of aneurysms took part. The goal was to see which treatment works b…

This study looked at how safe and effective the OPTIMA coil system is for treating brain aneurysms. Researchers followed 300 patients across Europe for up to 12 months after the coiling procedure. They tracked complications like bleeding, blood clots, and the need for repeat trea…

This study investigates whether people with late-onset Pompe disease have a higher risk of severe blood vessel problems in the brain and aorta. Researchers will collect medical and genetic data from adults with Pompe disease and from those who have had a brain aneurysm or bleedin…

This small pilot study tested whether a non-invasive eye scan called OCTA can detect changes in the brain related to stroke and other neurological conditions. Researchers compared eye scans from 7 people with brain diseases and healthy volunteers. The goal was to gather early dat…

This study tested a software tool called AneurysmFlow that measures blood flow in brain aneurysms. The goal was to see if it can predict whether an aneurysm will fully close 12 months after a stent is placed. 132 adults with unruptured brain aneurysms participated. The tool is al…