IMMUNOTHERAPY

This study tested whether adding the experimental drug lorigerlimab to standard chemotherapy (docetaxel) can delay cancer growth in men with a type of advanced prostate cancer that no longer responds to hormone therapy. About 150 participants received either the combination or ch…

This study tested a treatment called oral immunotherapy for people with shrimp allergy. 20 participants aged 12 to 40 with confirmed shrimp allergy were given small, increasing amounts of shrimp over time. The goal was to see if this approach could raise the amount of shrimp they…

This study tested whether adding the immunotherapy drug serplulimab to standard chemotherapy before and after surgery helps people with stage II-IIIA non-small cell lung cancer. 30 patients received the combination treatment. The main goal was to see how many had a major response…

This study tested whether adding immunotherapy to standard chemoradiation helps people with a certain type of ultra-low rectal cancer (MSS type) avoid permanent colostomy. About 200 patients who wanted to keep their anus were enrolled. The main goal was to see how many achieved a…

This early-stage study tested a treatment made from a patient's own tumor-fighting immune cells, called tumor-infiltrating lymphocytes (TILs). It included 43 adults with advanced solid tumors like melanoma, cervical cancer, and lung cancer. The goal was to find the safest dose an…

This study tested whether giving a chemotherapy drug (dacarbazine) before immunotherapy can help patients with advanced melanoma who did not respond to standard immunotherapy. 38 adults with a specific type of melanoma (BRAF wildtype) that had stopped responding to treatment were…

This study created and tested an educational website to help Black and African American cancer patients understand personalized cancer treatments and clinical trials. Researchers interviewed 48 patients and caregivers, then tested the website with 33 patients. The goal was to see…

This study looked at 42 adults with advanced solid tumors who were already on or about to start immunotherapy (checkpoint inhibitors) and also needed palliative radiotherapy to ease symptoms like pain or breathing trouble. The goal was to see how safe the combination is and wheth…

This study followed 44 adults with leukemia or lymphoma who received CAR T-cell therapy to see how their hearts were affected. Researchers used heart scans, blood tests, and quality-of-life surveys to track heart function over time. The goal was to find out how often heart proble…

This study tested whether a special DNA test (epigenetics multi-omics sequencing) can predict how well immunotherapy works for people with stomach or rectal cancer. 189 patients took part. The goal was to see if the test could tell who would have a complete response to treatment.…