Immunoglobulin G4-related disease
Clinical trials for Immunoglobulin G4-related disease explained in plain language.
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Can a JAK inhibitor boost remission in IgG4-Related disease?
Disease control CompletedResearchers are testing whether adding tofacitinib to prednisone works better than prednisone alone for people with active IgG4-related disease. The trial enrolls 58 adults with active disease and assigns them to either tofacitinib plus prednisone or prednisone alone. The main go…
Matched conditions: IMMUNOGLOBULIN G4-RELATED DISEASE
Sponsor: Peking University People's Hospital • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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New drug combo shows promise for rare autoimmune disease
Disease control CompletedThis study tested a new drug called rilzabrutinib combined with steroids in 27 adults with active IgG4-related disease, a rare condition causing inflammation and organ damage. The goal was to see if the combination could prevent disease flares better than steroids alone. Particip…
Matched conditions: IMMUNOGLOBULIN G4-RELATED DISEASE
Phase 2 • Sponsor: Principia Biopharma, a Sanofi Company • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC