IDH2 GENE MUTATION
Clinical trials for IDH2 GENE MUTATION explained in plain language.
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New hope for young brain tumor patients: drug duo targets genetic mutations
Disease control OngoingThis early-stage study tests a new drug (BGB-290) combined with chemotherapy (temozolomide) in adolescents and young adults with IDH1/2-mutant gliomas, a type of brain tumor. The goal is to find the safest dose and check for side effects. About 78 participants with newly diagnose…
Matched conditions: IDH2 GENE MUTATION
Phase: PHASE1 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 26, 2026 08:09 UTC
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New drug probe aims to measure niraparib's brain tumor penetration
Knowledge-focused OngoingThis early-stage trial enrolls 16 adults with recurrent IDH-mutant gliomas who are scheduled for surgery. Participants take niraparib for one month before their operation so researchers can measure how much drug reaches the tumor and how it affects cancer cells. The goal is to ga…
Matched conditions: IDH2 GENE MUTATION
Phase: EARLY_PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC