IDH2 GENE MUTATION
Clinical trials for IDH2 GENE MUTATION explained in plain language.
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New hope for young brain tumor patients: drug combo targets IDH mutations
Disease control OngoingThis early-phase study tests a new drug (BGB-290) combined with chemotherapy (temozolomide) in teens and young adults with a type of brain tumor called glioma that has an IDH mutation. The goal is to find the safest dose and see how well the combination works for both newly diagn…
Matched conditions: IDH2 GENE MUTATION
Phase: PHASE1 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 22, 2026 11:54 UTC
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New drug probe aims to measure niraparib's brain tumor penetration
Knowledge-focused OngoingThis early-stage trial enrolls 16 adults with recurrent IDH-mutant gliomas who are scheduled for surgery. Participants take niraparib for one month before their operation so researchers can measure how much drug reaches the tumor and how it affects cancer cells. The goal is to ga…
Matched conditions: IDH2 GENE MUTATION
Phase: EARLY_PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC