IDH wildtype glioblastoma
Clinical trials for IDH wildtype glioblastoma explained in plain language.
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Can a drug duo prime the brain to fight aggressive tumors?
Disease control Not yet recruitingThis trial is testing whether two oral drugs, avutometinib and defactinib, can be safely given to people with newly diagnosed high-grade gliomas, a type of aggressive brain cancer. Participants first take the drugs for one cycle before starting standard radiation, and those with …
Matched conditions: IDH WILDTYPE GLIOBLASTOMA
Early phase 1 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Can a seizure drug outsmart a deadly brain tumor?
Disease control Not yet recruitingThis trial tests whether adding levetiracetam, a seizure medication, to the standard treatment for glioblastoma can improve outcomes. Glioblastoma is an aggressive brain cancer with poor survival despite current therapy. The study focuses on tumors with low oxygen levels, which a…
Matched conditions: IDH WILDTYPE GLIOBLASTOMA
Phase 2 • Sponsor: Tianjin Medical University General Hospital • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC